Clinical Applications
RFS in stenotic lesions
Step 1: Atherosclerosis is the accumulation of fats, cholesterol, and other substances in the artery walls, forming plaque that can narrow arteries and block blood flow.
Step 2: The RFS overcomes atherosclerotic narrowing by providing a temporary vascular support structure to instantly restore normal blood flow.
Step 3: Finally, the RFS transforms into a new living artery while the implant gradually resorbs over time.
Chronic Limb Threatening Ischemia (CLTI)
Peripheral Artery Disease (PAD) is a condition where narrowed arteries reduce blood flow to the limbs, particularly the legs. Chronic Limb-Threatening Ischemia (CLTI) is the most severe form of PAD, characterized by critically reduced blood flow that leads to chronic pain, non-healing wounds, or tissue loss. Without timely intervention, CLTI can result in limb amputation and significantly impacts the patient’s quality of life.
Flow-Limiting Dissections
Flow-limiting dissections, which occur when the inner wall of an artery tears and obstructs blood flow, can exacerbate the severity of Chronic Limb-Threatening Ischemia (CLTI) by further reducing blood circulation to the affected limb. These dissections often complicate existing arterial blockages, increasing the risk of non-healing wounds, pain, and tissue loss associated with CLTI. Without proper management, flow-limiting dissections can accelerate the progression toward limb amputation in patients with CLTI. Scaffolding with the RFS can solve this issue.